AutoSoft Systems
        AutoSoft Systems 2 Round Hill Court
        East Greenwich, RI 02818
        401.884.5653 Fax
                        401.996.3631 Cell
AMDG       Decision Ready Information! autosoft@aol.com
Commercial & custom multi-user computer software for a variety of applications including performance metrics, statistical analysis, data extraction and merger from multiple large databases, computer simulation and management information systems.  Founded in 1982.
We know Excel! Whenever possible, Excel is the user interface, VBA is the programming language, ODBC connects to the database of your choice.
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AutoDNA - Restriction Endonuclease Analysis
Biopharmaceutical production requires cell banks that are stable over many years.   One confirms that the cells' DNA is stable through periodic sampling.  Confirming that a cell bank is stable over several years is a bit tricky as standards change.  Also, the DNA of a cell is not characterized by a single point, but by a series of points on multiple lanes of a DNA ladder.  Proper definition of a standard could require 5O+ different data points on multiple lanes.  Analysis of a sample again is over multiple lanes and 50+ data points.  Significant statistics need to be applied to confirm the cell bank is stable, or to identify that the cell bank is changing with time.
The Main screen presents the user with instructions on how to proceed:
The Standards screen allows the user to calibrate the standards.
The HELP button reveals detailed instructions on how to proceed:
The DATA screen allows the user to enter the data, calculate and compare to historical data, and provides color coded feedback on the stability of the cell bank.  Note how the comments are used to provide detailed information on each data point.
The HELP button reveals detailed instructions on how to proceed:
Each lane has its own detail sheet with a full statistical analysis:
A comprehensive explanation is included as a comment for each statistic:
AutoSoft Systems | 2 Round Hill Court, East Greenwich, Rhode Island, USA 02818 | 401.885.3631 | Fax: 401.884.5653 | Mobile: 401.996.3631 
This web page was last updated at 02/21/2014 07:53 AM and is written in EXCEL!
AXIOM is a Trademark of Consona - USYS is a Trademark of Zumbach - AutoSoft Systems is not affiliated with Consona nor Zumbach